Publications · AJ Book

Peer reviewed

Original research

Thymic Composition Predicts Radiation Pneumonitis in Locally Advanced NSCLC

Chaunzwa TL, Krishnan G, Book AJ, Miller DG, Amoako-Boadu K, Garomsa B, Meng YJ, Yang E, Ma J, Chidi A, Gomez DR, Shaverdian N.

Journal of Thoracic Oncology. 2026;103949. doi:10.1016/j.jtho.2026.103949.
Critical Role of Keratinocytes and Protease-Activated Receptor 2 in Secondary Lymphedema Development

Park HJ, Pal S, Chen X, Shin J, García Nores GD, Baik JE, Stull-Lane A, Book AJ, Clement CC, Encarnacion EM, Klang MG, Riedel E, Chaunzwa TL, Hespe GE, Santambrogio L, Coriddi M, Dayan JH, Mehrara BJ, Kataru RP.

Clinical and Translational Medicine. 2026;16(6):e70682. doi:10.1002/ctm2.70682.
Cholangiocarcinoma, Sequential Chemotherapy, and Prognostic Tests

Bruckner HW, De Jager R, Knopf E, Bassali F, Book AJ, Gurell D, Nghiem V, Schwartz M, Hirschfeld A.

Frontiers in Oncology. 2024;14:1361420. doi:10.3389/fonc.2024.1361420.
Actionable Tests and Treatments for Patients with Gastrointestinal Cancers and Historically Short Median Survival Times

Bruckner HW, Bassali F, Dusowitz E, Gurell D, Book AJ, De Jager R.

PLOS ONE. 2022;17(11):e0276492. doi:10.1371/journal.pone.0276492.

Peer reviewed

Review & correspondence

From Stasis to Systematics: Deciphering the Pathophysiology of Secondary Lymphedema Through Omics

Stull-Lane AR, Chen X, Book AJ, Kratchmarov R, Pal S, Shin J, Ashokan G, Hespe GE, Mehrara BJ, Kataru RP.

Frontiers in Immunology. 2026;17:1850725. doi:10.3389/fimmu.2026.1850725.
Enhancing Toxicity Reporting with Objective Measures and Contemporary Tools

Bruckner HW, Knopf E, Book AJ, De Jager R.

JCO Oncology Practice. 2025;21(12):1891–1892. doi:10.1200/OP-25-00139.

Preprints

Publicly available manuscripts

Thymus Composition, Disease Control, and Toxicity in Locally Advanced Lung Cancer

Chaunzwa TL, Book AJ, Garomsa B, Meng YJ, Yang E, Krishnan G, Chidi A, Kim R, Ma J, Riely GJ, Huang J, Simone CB, Shaverdian N, Gomez DR.

medRxiv. 2025. doi:10.1101/2025.10.20.25338395.
Mechanistic Modeling and Machine Learning Identifies Optimum Radiotherapy Schedules to Prevent Treatment-Induced Metastasis

Graser CJ, Zhou Z, Schürch M, Moorhead G, Chaunzwa TL, Book AJ, Dean J, Lin C, Dean JA, Gomez D, Kozono D, Lahav G, Michor F.

bioRxiv. 2025. doi:10.1101/2025.07.02.662373. Manuscript also under review.

Current manuscripts

Under review

CT-Derived Thymic Involution Is Associated with a Peripheral CD8+ Inhibitory-Receptor Phenotype and Inferior Survival in Unresected Locally Advanced NSCLC

Miller DG*, Chaunzwa TL*, Book AJ*, Amoako-Boadu K, Krishnan G, Wu A, Gelblum DY, Okamura YT, Kagami S-I, Rimner A, Deasy JO, Simone CB II, Gomez DR, Chaft JE, Shaverdian N.

Manuscript under review, 2026. *Shared first authorship.
Mechanistic Modeling and Machine Learning Identifies Optimum Radiotherapy Schedules to Prevent Treatment-Induced Metastasis

Graser CJ, Zhou Z, Schürch M, Moorhead G, Chaunzwa TL, Book AJ, Dean J, Lin C, Dean JA, Gomez D, Kozono D, Lahav G, Michor F.

Manuscript under review, 2026. Preprint: bioRxiv doi:10.1101/2025.07.02.662373.

Current manuscripts

In preparation

CT-Derived Host Immuno-Metabolic Phenotyping Predicts Response to Neoadjuvant Chemoimmunotherapy in Resectable Locally Advanced NSCLC

Chaunzwa TL*, Yang E*, Book AJ*, Lee V, Krishnan G, Chitsike L, Amoako-Boadu K, Miller D, Xiong K, Meng J, Bott M, Schoenfeld A, Simone CB II, Gomez D, Chaft J, Shaverdian N.

Manuscript in preparation, 2026. *Shared first authorship.

Journal indexed

Published meeting abstracts

Conference abstracts published in journal supplements or proceedings, listed separately from full-length articles.

Show published meeting abstracts (12)

Leveraging large language models on personal computers for automated identification of lung cancer progression in radiology reports

Kim A, Miller DG, Lee V, Simhal AK, Meng YJ, Book AJ, Chidi A, Gomez DR, Chaunzwa TL.

2025 ASCO Quality Care Symposium. JCO Oncology Practice. 2025;21(10_suppl):624. doi:10.1200/OP.2025.21.10_suppl.624.
Routine prognostic blood tests to compare survival outcomes with low-dose therapy in treatment-naïve and resistant advanced pancreatic cancer

Bruckner HW, Knopf E, De Jager RL, Book AJ, Bassali F.

2026 ASCO Annual Meeting. Journal of Clinical Oncology. 2026;44(16_suppl):e16349. doi:10.1200/JCO.2026.44.16_suppl.e16349.
Role of routine prognostic blood tests in evaluating chances of safely prolonged survival across all ages

De Jager RL, Knopf E, Bassali F, Book AJ, Bruckner HW.

2026 ASCO Annual Meeting. Journal of Clinical Oncology. 2026;44(16_suppl):e16348. doi:10.1200/JCO.2026.44.16_suppl.e16348.
Predictive blood tests identify patients who achieve prolonged survival with low-dose multi-drug chemotherapy in new and resistant pancreatic cancers

Bruckner HW, Knopf E, De Jager R, Book AJ, Bassali F.

Annals of Oncology. 2025;36:S1927. Published meeting abstract.
Blood tests identify expanded eligibility and prolonged survival across all ages

De Jager R, Book AJ, Knopf E, Bassali F, Bruckner HW.

SIOG 2025 Annual Conference. Journal of Geriatric Oncology. 2025;16(8 Suppl):102439. doi:10.1016/j.jgo.2025.102439.
Practical tests and 5th line treatments for real-world elderly with ovarian cancer

Bruckner HW, Knopf E, Bassali F, Book AJ, De Jager R.

International Society of Geriatric Oncology Annual Conference. Journal of Geriatric Oncology. 2023;14(8):S14. doi:10.1016/S1879-4068(23)00281-3.
Blood tests predict safe survival of elderly with resistant GI cancers

Bruckner HW, Hirschfeld A, DeJager R, Bassali F, Gurell D, Nghiem V, Dusowitz E, Distenfeld S, Schwartz M, Book AJ.

International Society of Geriatric Oncology Annual Conference. Journal of Geriatric Oncology. 2021;12(8):S51. doi:10.1016/S1879-4068(21)00427-6.
Moderate dose serial therapy for aged and resistant patients with cholangiocarcinomas

Bruckner HW, Hirschfeld A, De Jager RL, Bassali F, Gurell D, Nghiem V, Book AJ, Distenfeld S, Schwartz ME.

2021 ASCO Annual Meeting. Journal of Clinical Oncology. 2021;39(15_suppl):e16160. doi:10.1200/JCO.2021.39.15_suppl.e16160.
Blood tests to predict one- to two-year survival of patients with difficult cancers

De Jager RL, Bruckner HW, Bassali F, Dusowitz E, Book AJ, Distenfeld S, Hirschfeld A.

2021 ASCO Annual Meeting. Journal of Clinical Oncology. 2021;39(15_suppl):e16158. doi:10.1200/JCO.2021.39.15_suppl.e16158.
Survival and prognostic tests in a real-world phase II experience with a safe, moderate-dose, sequential chemotherapy algorithm for metastatic pancreatic adenocarcinoma

De Jager RL, Bruckner HW, Bassali F, Hirschfeld A, Gurell D, Nghiem V, Distenfeld S, Weinberger NS, Book AJ.

2020 ASCO Annual Meeting. Journal of Clinical Oncology. 2020;38(15_suppl):e16763. doi:10.1200/JCO.2020.38.15_suppl.e16763.
Moderate sequential third- to fourth-line chemotherapy algorithms for the elderly with resistant colorectal cancer

De Jager R, Bruckner HW, Hirschfeld A, Gurell D, Nghiem V, Book AJ, Distenfeld S, Weinberger NS.

SIOG 2019 Annual Conference. Journal of Geriatric Oncology. 2019;10(6):S47–S48. doi:10.1016/S1879-4068(19)31196-8.
Moderate dose sequential chemotherapy algorithms for the elderly with and without resistant cancers

Bruckner HW, Hirschfeld A, De Jager R, Bassali F, Gurell D, Nghiem V, et al.

SIOG 2019 Annual Conference. Journal of Geriatric Oncology. 2019;10(6):S39. doi:10.1016/S1879-4068(19)31181-6.

Presentations

Selected posters & accepted abstracts

StageBridge Resolves Inflammatory-Stromal Transition Niches in Lung Adenocarcinoma Progression

Book AJ, Oh JH, Simhal AK, Deasy JO, Guven E, Chaunzwa TL, Bradburne C.

Poster presented at the Center for Tumor Immune Systems Biology Symposium, Sloan Kettering Institute, 2026.
CT-Based Integrated Body Phenotyping Captures Host Susceptibility to Radiation Pneumonitis in Locally Advanced NSCLC

Xiong K, Krishnan G, Amoako-Boadu K, Book AJ, Miller DG, Yang E, Lee V, Meng J, Chidi AP, Chaft JE, Shaverdian N, Chaunzwa TL.

Accepted abstract, IASLC World Conference on Lung Cancer, 2026.
CT-Derived Host Immuno-Metabolic Phenotyping Predicts Response to Neoadjuvant Chemoimmunotherapy in Resectable Locally Advanced NSCLC

Yang E, Chaunzwa TL, Lee V, Book AJ, et al.

Accepted abstract, IASLC World Conference on Lung Cancer, 2026.
CT-Derived Multi-Organ Host Phenotyping of Never-Smoking Women with Lung Cancer

Glovinsky ER, Book AJ, Krishnan G, Chaunzwa TL.

Accepted abstract, MSK Cancer Engineering Symposium, 2026.
Exploring a Novel CT-Derived Immuno-Structural Marker for Radiation Pneumonitis in Lung Cancer

Garomsa B, Book AJ, Chaunzwa TL.

Lightning talk, 15th AORTIC International Conference on Cancer in Africa, Hammamet, Tunisia, 2025.