Computational & Systems Biology
Research Assistant, Memorial Sloan Kettering Cancer Center
I study how inflammatory, age-associated, and treatment history shape immune and tissue states. My work combines quantitative imaging, single-cell and spatial genomics, and interpretable modeling to recover biological state from sparse human data.
At MSK, I develop imaging-derived host phenotypes and connect them to immune, genomic, treatment, and outcome data. My M.S. thesis at Johns Hopkins focused on regulatory progression from cross-sectional spatial and single-nucleus transcriptomics.
M.S. Bioinformatics, Johns Hopkins University (2026) · B.A. Biochemistry, Yeshiva University (2023)
Current work
Selected projects that represent my work in quantitative imaging, regulatory genomics, and systems biology.
Method development · MSK
I conceived and engineered HostBio, an interpretable probabilistic framework for recovering host-tissue composition from routine CT. The framework is implemented for MSK clinical research and has been evaluated across 1,078 patients in four independent NSCLC cohorts, including randomized RTOG-0617, using immune, genomic, treatment, toxicity, response, and survival data.
1,078 patients · 4 NSCLC cohorts · randomized trial data
Explore HostBio →
M.S. thesis · Johns Hopkins
I developed StageBridge to test what aspects of epithelial progression can be inferred from cross-sectional spatial and single-nucleus transcriptomics. A hidden recoverability failure led me to reformulate the model around conditional transport, improving transition recoverability from 0.27 to 0.84; external PanIN testing returned a calibrated null where the data did not support reliable transition structure.
Recoverability 0.27 → 0.84 · donor-held-out testing · calibrated external null
Explore StageBridge →
Published collaborative research · MSK
My published work with the Mehrara laboratory includes a peer-reviewed study of keratinocyte and PAR2 biology in secondary lymphedema and a systems-level review of how omics approaches are reshaping the field.
Clinical and Translational Medicine · Frontiers in Immunology · 2026
Explore published lymphedema work →Selected outputs
CT-Derived Thymic Involution Is Associated with a Peripheral CD8+ Inhibitory-Receptor Phenotype and Inferior Survival in Unresected Locally Advanced NSCLC
Thymic Composition Predicts Radiation Pneumonitis in Locally Advanced NSCLC
Critical Role of Keratinocytes and Protease-Activated Receptor 2 in Secondary Lymphedema Development