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Published collaborative research · Secondary lymphedema

Secondary lymphedema

Published work on persistent inflammatory tissue remodeling and the molecular biology of secondary lymphedema.

Published secondary lymphedema figure showing epidermal inflammatory remodeling and cell-specific PAR2 biology
Published findings on epidermal inflammatory remodeling and PAR2 biology in secondary lymphedema. Adapted from Park et al., Clinical and Translational Medicine (2026), CC BY 4.0.
RoleComputational collaborator
LaboratoryMehrara Laboratory, MSK
Published workOriginal research + review
FocusInflammation and tissue remodeling

I contributed to a peer-reviewed study identifying a critical role for keratinocytes and protease-activated receptor 2 in secondary lymphedema development.

The work links epidermal inflammatory remodeling with cell-specific PAR2 biology and provides a mechanistic framework for understanding how epithelial responses contribute to chronic lymphatic disease.

Read the paper →

I also co-authored a peer-reviewed review examining how transcriptomic, proteomic, single-cell, and related omics approaches are reshaping the study of secondary lymphedema pathophysiology.

The review focuses on moving beyond fluid stasis as a complete explanation of disease toward a systems-level view of persistent epithelial, stromal, immune, and lymphatic remodeling.

Read the review →